The Bradley Lab

Our long-term aim is to understand the gut microbiome as well as we currently understand model microbes, using both computational and high-throughput experimental tools. This understanding will allow us to interpret and eventually to modulate human microbiomes more precisely. We are part of Ohio State’s Department of Microbiology, Infectious Diseases Institute, and Center of Microbiome Science.

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The Bradley Lab

Latest News

Feb 17, 2024 1 min read
Combustion, Conversation, and Condados
Combustion, Conversation, and Condados

Thanks everyone for coming out to the Happy Hour! It’s always awesome to catchup and hear what everyone is doing.
Feb 3, 2024 1 min read
Welcome to New Graduate Student

We are excited to have a new PhD student in our group, Alexis Young. Welcome to the group, Alexis!
Jan 3, 2024 1 min read
Congratulations on The Grant!

A big congratulations to Patrick for being awarded the AFRL seed grant! Great work!
Nov 17, 2023 1 min read
Bradley Lab Happy Hour
Bradley Lab Happy Hour

Was great to have everyone join in the fun! Glad people could make it out
Oct 26, 2023 1 min read
Pets, Fall, and Microbiology

Was fun having everyone come out the Understory for the happy hour. Had a great time talking about science and life! Looking forward to having the group out again soon. Thanks to Bradley for catching the tab.
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Featured Projects

phylogenize
Find genes underlying microbial environment associations with phylogenize
phylogenize

Recent Publications

Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism
Pharmaceuticals have extensive reciprocal interactions with the microbiome, but whether bacterial drug sensitivity and metabolism is …
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phylogenize: correcting for phylogeny reveals genes associated with microbial distributions
Phylogenetic comparative methods are powerful but presently under-utilized ways to identify microbial genes underlying differences in …
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Minor isozymes tailor yeast metabolism to carbon availability
Isozymes are enzymes that differ in sequence but catalyze the same chemical reactions. Despite their apparent redundancy, isozymes are …
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Phylogeny-corrected identification of microbial gene families relevant to human gut colonization
The mechanisms by which different microbes colonize the healthy human gut versus other body sites, the gut in disease states, or other …
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Proteobacteria explain significant functional variability in the human gut microbiome
BACKGROUND While human gut microbiomes vary significantly in taxonomic composition, biological pathway abundance is surprisingly …
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