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A new system for comparative functional genomics of *Saccharomyces* yeasts
Whole-genome sequencing, particularly in fungi, has progressed at a tremendous rate. More difficult, however, is experimental testing …
Amy a Caudy
,
Yuanfang Guan
,
Yue Jia
,
Christina Hansen
,
Chris DeSevo
,
Alicia P Hayes
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Joy Agee
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Juan R Alvarez-Dominguez
,
Hugo Arellano
,
Daniel Barrett
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Cynthia Bauerle
,
Namita Bisaria
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Patrick H Bradley
,
J Scott Breunig
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Erin Bush
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David Cappel
,
Emily Capra
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Walter Chen
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John Clore
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Peter a Combs
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Christopher Doucette
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Olukunle Demuren
,
Peter Fellowes
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Sam Freeman
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Evgeni Frenkel
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Daniel Gadala-Maria
,
Richa Gawande
,
David Glass
,
Samuel Grossberg
,
Anita Gupta
,
Latanya Hammonds-Odie
,
Aaron Hoisos
,
Jenny Hsi
,
Yu-Han Huang Hsu
,
Sachi Inukai
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Konrad J Karczewski
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Xiaobo Ke
,
Mina Kojima
,
Samuel Leachman
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Danny Lieber
,
Anna Liebowitz
,
Julia Liu
,
Yufei Liu
,
Trevor Martin
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Jose Mena
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Rosa Mendoza
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Cameron Myhrvold
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Christian Millian
,
Sarah Pfau
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Sandeep Raj
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Matt Rich
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Joe Rokicki
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William Rounds
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Michael Salazar
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Matthew Salesi
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Rajani Sharma
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Sanford Silverman
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Cara Singer
,
Sandhya Sinha
,
Max Staller
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Philip Stern
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Hanlin Tang
,
Sharon Weeks
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Maxwell Weidmann
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Ashley Wolf
,
Carmen Young
,
Jie Yuan
,
Christopher Crutchfield
,
Megan McClean
,
Coleen T Murphy
,
Manuel Llinás
,
David Botstein
,
Olga G Troyanskaya
,
Maitreya J Dunham
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Phylogenetic portrait of the *Saccharomyces cerevisiae* functional genome
The genome of budding yeast (Saccharomyces cerevisiae) contains approximately 5800 protein-encoding genes, the majority of which are …
Patrick A. Gibney
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Mark J. Hickman
,
Patrick H. Bradley
,
John C. Matese
,
David Botstein
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DOI
Yeast cells can access distinct quiescent states
We conducted a phenotypic, transcriptional, metabolic, and genetic analysis of quiescence in yeast induced by starvation of …
Maja M Klosinska
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Christopher a Crutchfield
,
Patrick H Bradley
,
Joshua D Rabinowitz
,
James R Broach
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Growth-limiting intracellular metabolites in yeast growing under diverse nutrient limitations
Microbes tailor their growth rate to nutrient availability. Here, we measured, using liquid chromatography-mass spectrometry, …
Viktor M. Boer
,
Christopher A. Crutchfield
,
Patrick H. Bradley
,
David Botstein
,
Joshua D. Rabinowitz
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Coordinated concentration changes of transcripts and metabolites in *Saccharomyces cerevisiae*
Metabolite concentrations can regulate gene expression, which can in turn regulate metabolic activity. The extent to which functionally …
Patrick H Bradley
,
Matthew J Brauer
,
Joshua D Rabinowitz
,
Olga G Troyanskaya
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