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Automated and accurate estimation of gene family abundance from shotgun metagenomes
Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial …
Stephen Nayfach
,
Patrick H. Bradley
,
Stacia K. Wyman
,
Timothy J. Laurent
,
Alex Williams
,
Jonathan A. Eisen
,
Katherine S. Pollard
,
Thomas J. Sharpton
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Phylogenetic portrait of the *Saccharomyces cerevisiae* functional genome
The genome of budding yeast (Saccharomyces cerevisiae) contains approximately 5800 protein-encoding genes, the majority of which are …
Patrick A. Gibney
,
Mark J. Hickman
,
Patrick H. Bradley
,
John C. Matese
,
David Botstein
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Yeast cells can access distinct quiescent states
We conducted a phenotypic, transcriptional, metabolic, and genetic analysis of quiescence in yeast induced by starvation of …
Maja M Klosinska
,
Christopher a Crutchfield
,
Patrick H Bradley
,
Joshua D Rabinowitz
,
James R Broach
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Coordinated concentration changes of transcripts and metabolites in *Saccharomyces cerevisiae*
Metabolite concentrations can regulate gene expression, which can in turn regulate metabolic activity. The extent to which functionally …
Patrick H Bradley
,
Matthew J Brauer
,
Joshua D Rabinowitz
,
Olga G Troyanskaya
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