Genomics

Human xenobiotic metabolism proteins have full-length and split homologs in the gut microbiome
Xenobiotics, including pharmaceutical drugs, can be metabolized by both host and microbiota, in some cases by homologous enzymes. We …
PDF Cite DOI
Minor isozymes tailor yeast metabolism to carbon availability
Isozymes are enzymes that differ in sequence but catalyze the same chemical reactions. Despite their apparent redundancy, isozymes are …
Cite DOI
Automated and accurate estimation of gene family abundance from shotgun metagenomes
Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial …
PDF Cite DOI
Coordinated concentration changes of transcripts and metabolites in *Saccharomyces cerevisiae*
Metabolite concentrations can regulate gene expression, which can in turn regulate metabolic activity. The extent to which functionally …
PDF Cite DOI