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Human xenobiotic metabolism proteins have full-length and split homologs in the gut microbiome
Xenobiotics, including pharmaceutical drugs, can be metabolized by both host and microbiota, in some cases by homologous enzymes. We …
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Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses
Individual genes from microbiomes can drive host-level phenotypes. To help identify such candidate genes, several recent tools estimate …
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Adaptive adjustment of significance thresholds produces large gains in microbial gene annotations and metabolic insights
Gene function annotations enable microbial ecologists to make inferences about metabolic potential from genomes and metagenomes. …
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