Microbiome

Phylogenize2: robust phylogenetic methods link genes to phenotypes across host-associated and environmental microbiomes
In microbiome studies, associations between microbial functions and the environment are often confounded by phylogeny. While some …
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A robust, sensitive phylogenetic method enables gene-level metagenomic analyses
A key goal in the microbiome field is to move from taxonomic associations towards mechanistic hypotheses about microbial gene function. …
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Berry Supplement-Modified Human Microbiome Improves Immunotherapy Response in Mouse Models
Cancer outcomes have improved with immune checkpoint inhibitor (ICI) treatment; however, less than half of tumors respond. Emerging …
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Four-part harmony between diet, drugs, microbes, and host
In this issue of Cell Host & Microbe, Zeng et al. show that a specific gut microbe causes diet-dependent attenuation of …
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Building a chemical blueprint for human blood
What determines the chemical make-up of human blood? Measurement of the contributions of factors ranging from genetics to lifestyle has …
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Phylogeny-corrected identification of microbial gene families relevant to human gut colonization
The mechanisms by which different microbes colonize the healthy human gut versus other body sites, the gut in disease states, or other …
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Automated and accurate estimation of gene family abundance from shotgun metagenomes
Shotgun metagenomic DNA sequencing is a widely applicable tool for characterizing the functions that are encoded by microbial …
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