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Phylogenetics
Phylogenize2: robust phylogenetic methods link genes to phenotypes across host-associated and environmental microbiomes
In microbiome studies, associations between microbial functions and the environment are often confounded by phylogeny. While some …
Kathryn Kananen
,
Nghi Tran
,
Patrick H. Bradley
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A robust, sensitive phylogenetic method enables gene-level metagenomic analyses
A key goal in the microbiome field is to move from taxonomic associations towards mechanistic hypotheses about microbial gene function. …
Nghi Tran
,
Kathryn Kananen
,
Patrick H. Bradley
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Phylogeny-corrected identification of microbial gene families relevant to human gut colonization
The mechanisms by which different microbes colonize the healthy human gut versus other body sites, the gut in disease states, or other …
Patrick H. Bradley
,
Stephen Nayfach
,
Katherine S. Pollard
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