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Statistical Methods
A robust, sensitive phylogenetic method enables gene-level metagenomic analyses
A key goal in the microbiome field is to move from taxonomic associations towards mechanistic hypotheses about microbial gene function. …
Nghi Tran
,
Kathryn Kananen
,
Patrick H. Bradley
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Framework for exploring the sensory repertoire of the human gut microbiota
Bacteria sense changes in their environment and transduce signals to adjust their cellular functions accordingly. For this purpose, …
Patricia A. Ross
,
Wenhao Xu
,
Ekaterina Jalomo-Khayrova
,
Gert Bange
,
Vadim M. Gumerov
,
Patrick H. Bradley
,
Victor Sourjik
,
Igor B. Zhulin
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DOI
Proteobacteria explain significant functional variability in the human gut microbiome
BACKGROUND While human gut microbiomes vary significantly in taxonomic composition, biological pathway abundance is surprisingly …
Patrick H. Bradley
,
Katherine S. Pollard
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